Propolis is derived from a tree resin which is collected and re-metabolised by worker bees. The bees smear this dark substance around the entrance of their hives to strengthen the hive and to protect themselves from infection. Excess propolis is extracted from the beehive by bee keepers. A cold treatment process is then applied to make the substance suitable for human use and consumption. Propolis Propolis contains natural antioxidant bioflavonoids. Collected by bees, propolis has mild antibacterial and antibiotic characteristics. Propolis contains over 60 different naturally occurring substances, including flavonoids, organic acids, vitamins and numerous minerals.